We only have limited understanding of the exquisite ways in which everything on Earth is interconnected. Suppose environmental assessments had been conducted before we sprayed DDT onto open fields or topped up spray cans with CFCs. We didn't know about bio-magnification or chlorine degradation of the ozone layer until long after these technologies were approved. This is a fundamental problem. We can't anticipate long-term consequences of any major technology if we are ignorant of how the world works and too impatient to invest the time and effort to learn more through scientific research.